3-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]benzoic acid - Names and Identifiers
Name | 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl)ester
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Synonyms | N-BOC-4-(3-CARBOXYPHENYL) PIPERIDINE 1-BOC-4-(3-CARBOXY-PHENYL)-PIPERIDINE 3-(1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)BENZOIC ACID 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-di... 4-(3-Carboxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester 3-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]benzoic acid 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl)ester 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl) ester
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CAS | 828243-30-7
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3-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]benzoic acid - Physico-chemical Properties
Molecular Formula | C17H23NO4
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Molar Mass | 305.37 |
Storage Condition | 2-8°C |
3-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]benzoic acid - Introduction
1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl)ester(1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl Boc-Phe-Pip-OtBu) ester). The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: White solid
-Molecular formula: C22H27NO4
-Molecular weight: 369.46g/mol
-Melting point: 50-54°C
-Boiling Point: 564.5°C at 760 mmHg
-Solubility: Soluble in some organic solvents, such as dimethylformamide, dichloromethane, etc.
Use:
- 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl)ester is a commonly used organic synthesis reagent.
-It can be used as a reagent for protecting amino acids, and used to protect the N-terminal amino acids in peptide synthesis.
-It can also be used in the synthesis of drugs, pesticides, natural products and other organic compounds.
Preparation Method:
The preparation of 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimenthylethyl) ester usually uses the following steps:
1.4-carboxyl-benzoic acid is heated to react with sulfurous acid to form sulfoxide acid.
2. Sulfoxide and 1-piperidinmethanol were esterified to obtain the esterified product.
3. The esterification product is reacted with tributyl aluminum hydroxide to generate the target compound 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl)ester.
Safety Information:
- 1-Piperidinecarboxylic acid, 4-(3-carboxyphenyl)-, 1-(1,1-dimethylethyl)ester is an organic compound, which needs to be safe during operation.
-It may be irritating to the skin, eyes and respiratory tract. Wear protective gloves and glasses and ensure good ventilation.
-Avoid contact with oxidants, high temperatures and open flames during storage and handling to prevent the risk of fire and explosion.
-In case of inhalation or contact, rinse immediately with water and seek medical examination.
-In the laboratory or industrial production, safety protection should be carried out according to the specific situation and follow the relevant operating procedures.
Last Update:2024-04-09 19:05:52